|
Three major different b- Glucan fractions can be obtained from the Yeast Cell Wall: - An alkaline soluble fraction which constitutes about 20% of the Yeast Cell Wall. 80 – 85 % of this component is ß-(1,3)-Glucan, 8 – 12 % is ß-(1,6)-Glucan. - An alkaline insoluble Glucan fraction consisting of 85 % ß-(1,3)-Glucan and about 3% ß-(1,6)-Glucan. The long b-(1,3)-Glucan backbone chains are interrupted with b-(1,6)-Glucan side chains at intervals. Inter- and intra-molecular hydrogen-bonding leads to the highly stable, insoluble structure. - A second alkaline insoluble fraction is highly branched with ß-(1,6)- and ß-(1,3) bonding. This fraction can be extracted with acetic acid. Depending on the chain length and the interval of the side chains, there is partial helix structure to the b-(1,3)- backbone of the b-Glucan.
|